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The Life Sciences Institute is a research centre dedicated to the understanding of fundamental biological pathways in human health and disease, environmental science and industrial processes.

We promote scientific discovery through creative and multidisciplinary approaches in an environment that is highly collaborative. We also seek to integrate our pioneering basic research with the application and exploitation of new research discoveries. LSI brings together scientists and clinicians from five NUS faculties and supports advanced core facilities and cutting-edge research infrastructure.

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New Appointments

New Appointments

A/Prof Hyungwon Choi, the director of SLING since August 2023, has been appointed Chair of Cardiovascular Metabolic Diseases Translational Research Programme (CVMD TRP). He will integrate his systems biology and multi-omic clinical biomarker research portfolio with the TRP's expanding basic science and clinical research programs.

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New Appointment

New Appointment

Renowned scientist Professor Rickie Patani takes on the role of Director of the Neurobiology Programme at the Life Sciences Institute at NUS.

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New Programmatic Grant

New Programmatic Grant

In 2025, SLING was awarded a new round of funding for a Phase II project under the same grant scheme, worth S$7.67M (main PI Federico Torta). The project is entitled "BioMEX - Biomonitoring of Metabolic Health and Exposome at the NUS-Agilent Hub".

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New Appointment

New Appointment

Associate Professor ZHANG Yongliang has been appointed Director of the LSI Immunology Programme, effective July 2025. He concurrently holds the position of NUSMed Immunology TRP Chair.

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Matthew Chang

Boosting the global bioeconomy

Assoc Prof Matthew Chang, Director of the NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI), is one of five key members of global Task Force on Engineering Biology Metrics and Technical Standards for the Global Bioeconomy.

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Karishma

Decoding Asian Disease Phenotypes

Immunologists from the University of Cambridge and the LSI Immunology Programme at NUS have established a joint centre dedicated to high-resolution cell and molecular phenotyping.

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Research Highlights


Dr Vincenzo Sorrentino

NAD+ and mitochondria in ageing and disease
(Nature 2025)

News and Views


NUS Life Sciences Institute (LSI) Neurobiology Research Programme in collaboration with IDG Capital and several well renowned education institutions organised the NeuroFrontiers Symposium in January 2025 at the NUS University Cultural Centre. You can read more here.

Research teams led by Professor Barry Halliwell, Programme Leader of LSI Neurobiology Programme, revealed that low levels of ergothioneine (ET) in blood plasma may predict an increased risk of cognitive impairment and dementia, suggesting possible therapeutic or early screening measures for cognitive impairment and dementia in the elderly. You can read it here.