The LSI Neurobiology Programme consists of a broad-based group of investigators who conduct inter-disciplinary research that includes developmental and molecular neurobiology, the neurobiology of perception and cognition, age-related neurodegenerative diseases (especially Alzheimer’s and Parkinson’s disease) and stroke. NUS has made ageing and age-related diseases, especially neurodegenerative diseases, a major focus area. Members of the programme are drawn from a range of departments within and outside NUS.

Key Objectives

• To develop NUS as a world-class hub in Neurobiology and Ageing Research
• To act as a focus for the recruitment of talented academic staff members, researchers and postgraduates
• To pay special attention to neurological problems of relevance to Singapore and Asia

Research Areas

• Assessment and mechanisms of neurodegeneration (Combining cognitive, chemical, and imaging approaches)
• Origins of vascular dysfunction in Singapore
• Predictors of stroke and dementia
• Neuronal stem cells
• Neuronal lipidomics
• Proteasomal dysfunction, mitochondrial defects and oxidative damage in neurodegeneration
• Neuroprotective strategies
• Nematode and murine models of human ageing and neurodegenerative disease
• Cognitive neuroscience