Anne K Bendt
Deputy Director and Principal Investigator
Singapore Lipidomics Incubator (SLING), Life Sciences Institute
Tel: +65 6516 6683
Email: anne.bendt@nus.edu.sg

What are your present research interests?

Clinical mass spectrometry, lipidomics & metabolomics, precision medicine (cardiometabolic health, fertility), the ‘forever chemicals’ PFAS and population biomonitoring; innovation management; community outreach.

Do you have a distinctive viewpoint to your research?

I am driven by the challenge of translating research findings into applications with impact outside of the laboratory, in particular in the areas of healthcare.

What do you see as your future research directions?

1) Clinical applications of mass spectrometry for small molecules and toxins.
2) Robust workflows i.e. in compliance with relevant international standards such as ISO15189, to facilitate medical adoption.
3) Translation & Commercialization in the area of Precision Medicine and cardiometabolic health.

Does your laboratory have a particularly strong research expertise?

SLING is a worldwide leading program for mass spectrometry-based analysis of lipids, i.e. lipidomics. Recently, we expanded towards metabolites and environmental toxins. We further have a strong focus on education, and mutually beneficial partnerships with collaborating parties from academia and industry. Over the past two years, SLING has invested heavily in setting up ISO15189-compliant workflows for a select panel of analytes, to facilitate medical adoption.

Recent Publications

1) Narasimhan K, Vaitheeswari, Choi E, Chandran NS, Eriksson JG, Bendt AK, Torta F, Mir SA. Integrated analysis of per- and polyfluoroalkyl substances and plasma lipidomics profiles in multi-ethnic Asian subjects for exposome research. Environ Health. 2024. PMID: 39609840
2) Burla B, Oh J, Nowak A, Piraud N, Meyer E, Mei D, Bendt AK, Studt JD, Frey BM, Torta F, Wenk MR, Krayenbuehl PA. Plasma and platelet lipidome changes in Fabry disease. Clin Chim Acta. 2024. PMID: 38955246
3) Fux E, Lenski M, Bendt AK, Otvos JD, Ivanisevic J, De Bruyne S, Cavalier E, Friedecký D. A global perspective on the status of clinical metabolomics in laboratory medicine – a survey by the IFCC metabolomics working group. Clin Chem Lab Med. 2024. PMID: 38915248
4) Chen L, Goh XP, Bendt AK, Tan KM, Leow MK, Tan KH, Chan JKY, Chan SY, Chong YS, Gluckman PD, Eriksson JG, Wenk MR, Mir SA. Association of Acylcarnitines with Maternal Cardiometabolic Risk Factors Is Defined by Chain Length: The S-PRESTO Study. J Clin Endocrinol Metab. 2024. PMID: 38625914
5) Vogeser M, Bendt AK. From research cohorts to the patient – a role for “omics” in diagnostics and laboratory medicine? Clin Chem Lab Med. 2023. PMID: 36592431